Member Profile
Gbemisola Morounke Saibu
Country of origin: Nigeria Currently in: Nigeria, Lagos General field of specialization: Structural, Cell and Molecular Biology-
Degrees
2013 Doctorate Structural, Cell and Molecular Biology2001 Master Biological Systems and Organisms1996 Undergraduate Biological Systems and Organisms -
Current Research Activities
Structural, Cell and Molecular Biology
RESEARCH FOCUS With the increasing incidence of the various forms of cancers such as cervical cancers especially in the developing world such as Nigeria, coupled with the fact that cancer patients continue to explore alternative treatments, the need for reliable scientific data and extensive research with potentials for more effective and efficacious cancer prevention and treatment cannot be overemphasized. My research focus has been to promote and undertake cancer based researches with potentials to achieve the aforementioned. My research interest is broadly categorised as follows: 1. Basic research: aims to explore the mechanism and the molecular basis of cancer with a view to enhancing an understanding of how cancer develops and also provide the foundation for developing potential chemo prophylactic or therapeutic agents or diagnostic tests for cancers. 2. Translational research (drug discovery and development): aims to utilize the knowledge gained from basic research or the understanding of cancer biology to develop potential new treatments or diagnostic tests for various cancers. 3. Population and Behavioral research (Epidemiological research): aims to determine the burden of the various forms of cancers in Nigeria, identify the risks for cancers, and also look at how our behavior or lifestyles can predispose to or protect against cancers. 4. Research on Dietary influence in Cancer: aims to determine dietary pattern of Cancer patients and survivors in other to investigate the bioactive components of foods that could be beneficial to cancer patients.
Publications resulting from Research:
Saibu G.M., Katerere D. R., Rees D.J.G. and Meyer M (2015). In vitro cytotoxic and pro- apoptotic effects of water extracts of Tulbaghia violacea leaves and bulbs. Journal of Ethnopharmacology, 164: 203–209.
Saibu G.M., Sagar S., Green I., Ameer F. and Meyer M. (2014). Evaluating the cytotoxic effects of novel quinone compounds. Anticancer Research, 34: 4077- 4087.
Kazeem M.I., Ogungbe S.M., Saibu G.M. and Aboyade O. M. (2014). In vitro study on the hypoglycemic potential of Nicotiana tabacum leaf extracts Bangladesh J. Pharmacol. 9: 140-145.
Adu O.B., Ogundeko T.O., Ogunrinola O. O., Saibu G.M. and B. O. Elemo (2014). The effect of thermal processing on protein quality and free amino acid profile of Terminalia catappa (Indian Almond) Seed. J. Food Sci. Technol. DOI 10.1007/s13197-014-1490-8.
Motswainyana W. M., Onani M.O., Madiehe A. M. and Saibu G.M. (2014). Antitumor activity of phenylene bridged binuclear bis(imino-quinolyl) palladium(II) and Platinum(II) complexes. Bioorganic and Medicinal Chemistry Letters, 24 http://dx. doi.org/10.1016/j.bmcl.2014.02.056: 1692–1694.
Motswainyana W.M., Onani M.O, Madiehe A.M., Saibu G.M., Thovhogi N. and Lalancette R.A., (2013). Iminophosphine palladium(II) and platinum(II) complexes: Synthesis, molecular structures and evaluation as antitumor agents. Journal of Inorganic Biochemistry, doi: 10.1016/j.jinorgbio.2013.09.010:112–118
Motswainyana W.M., Onani M.O., Saibu G.M., Jacob J. and van Meervelt L. (2013). Imino-quinolyl palladium and platinum (II) complexes: Synthesis characterization, molecular structures and cytotoxic effect. Inorganic Chimica Acta, 400: 197-202.
Mahanga G., Joseph C., Nkunya M., Saibu G.M. Meyer M. and Mabusela W.T. (2013). Synthesis of hydroxy-p-menthanebenzyl mercaptans and their apoptotic activities. Molecules, 18 (1): 1-14.
Iwalokun B.A., Oyenuga A.O., Saibu G.M. and James A. (2011). Analyses of cytotoxic and genotoxic potentials of Loranthus micranthus using the Allium cepa test. Current Research Journal of Biological Sciences, 3(5): 459-467.
James, A.B., Saibu G.M., Magbagbeola O.A., Oloyo A.K. and Iwalokun B.A. (2011). The possible biochemical mechanism of action of petroleum -ether extract of Calotropis procera leaves (Asclepiadaceae)-A potent abortifacient in pregnant dawley rats. Asian Journal of Medical Sciences, 3(2): 61-66.
Ojekale A.B., Ojiako O.A., Saibu G.M., Lala A. and Olodude O.A. (2007). Long term effects of aqueous stem bark extract of Cissus populnea (Guill. And Per.) on some Biochemical Parameters in normal rabbit. African Journal of Biotechnology, 6 (3): 247-251.
Current profession
Current professional activities type:ResearchTeaching
Workshop and Conference Attended
2011 South Africa Research Capacity Development Workshop on Research Ethics, Introduction to Research, writing a successful grant proposal, Dissemination of Research results, Research Methodology and Introduction to ATLAS TAffiliations
American Society for Biochemistry and Molecular Biology (USA) (ASBMB)Nigerian Society of Biochemistry and Molecular BiologyAmerican Association for Cancer Research Associate Member (259734)African Organization for Research and Training in Cancer (AORTIC)The Association African Biomedical Scientists, IncPresentation given
2017Investigation for the presence of Genetic Polymorphism within the Estrogen Receptor-Α Promoter/Exon 1 Region and their effects on ESR1 expression in Cervical Cancer in LagosKigali, RwandaEvent: Poster presented at African organization for Research and Training in cancer (AORTIC) conference
