Member Profile
Membership type: full
PhD Fellowship
Ntsoaki Anna 'Nyane
Country of origin: Lesotho Currently in: South Africa, Durban General field of specialization: Medical and Health Sciences incl NeurosciencesPhD Fellowship
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Degrees
2017 Master Medical and Health Sciences incl Neurosciences -
Current Research Activities
Medical and Health Sciences incl Neurosciences
Identifying AMPK as a potential target of synthetic chalco-naringenin analogs and putative therapeutic applications.
Publications resulting from Research:
‘Nyane NA, Tlaila TB, Malefane TG, Ndwandwe DE, Owira PMO. Metformin-like antidiabetic, cardio-protective and non-glycemic effects of naringenin: Molecular and pharmacological insights. Eur J Pharmacol. 2017 May 15; 803:103-111
Current profession
Current professional activities type:ResearchDoing research on Naringenin, a flavonoid which exerts its antidiabetic effects by inhibition of gluconeogenesis through upregulation of AMPK, hence metformin-like effects. Because of these similar pharmacological effects between naringenin and metformin, our laboratory synthesized analogs of chlaco-naringenin compounds which could be more permeable to the plasma membrane and hence putatively increased pharmacological effects
Workshop and Conference Attended
December 2017 Abhu Dhabi IDF conferencePresentation given
2016AMPK as a potential target for synthetic chalco-naringenin analogs and putative therapeutic applicationsUKZN medical schoolEvent: CHS presentaions -
Fellowship with OWSD
Fellowship with OWSD
Fellowship awarded 2017
