Member Profile
Membership type: full
Alejandra Rodriguez-Haralambides
Country of origin: Uruguay Currently in: Uruguay, Montevideo General field of specialization: Chemical Sciences-
Degrees
1999 Doctorate Chemical Sciences1994 Master Chemical Sciences -
Current Research Activities
Chemical Sciences
Bioanalytical chemistry: Our focus is studying biochemical systems using Mass Spectrometry (LC-MSn). We work with natural products to evaluate their chemical profile and their potential bioactive compounds. Green Chemistry: Applying the principles of green chemistry/sustainable chemistry to our daily work and teaching. Food Safety and Authenticity: Trough their chemical profile, we study the authenticity and safety of food matrices.
Publications resulting from Research:
Natalia Oddone, Nicole Lecot, Marcelo Fernández, Alejandra Rodriguez‑Haralambides, Pablo Cabral, Hugo Cerecetto and Juan Claudio Benech; “In vitro and in vivo uptake studies of PAMAM G4.5 dendrimers in breast cancer”, J Nanobiotechnol 2016, 14:45
Krueger, D. ; Arora, S. ; Bzhelyansky, A. ; Chen, P. ; Chlenov, A. ; Collison, M. ; Durst, R. ; Es-Safi, N. E. ; Giancaspro, G. ; Hall, G. ; Hammerstone, J. ; Ingle, P. ; Jennens-Clough, M. ; Ji, D. ; Ji, J. ; Kennedy, D. ; Lawson, T. ; Lee, J. ; Lock, S. ; Mudge, E. ; Neal-Kababick, J. ; Phillips, M. ; Phillips, T. ; Rejaei, A. ; Rettinger, M. ; Rimmer, C. ; Rodriguez-Haralambides, A. ; Royce, S. ; Schaneberg; B. ; Solyom, A. ; Stern, N. ; Sullivan, D. ; Szpylka, J. ; Wise, M. ; Yan, X. ; Yoo, S-J. ; Yu, K. ; Zhang, Y, ; Coates, S. ; “Authentication of selected vaccinium species (anthocyanins) in dietary ingredients and dietary supplements”, Journal of AOAC International, 2015, Vol. 98, No. 4, 1052-1054, DOI : 10.5740/jaoac.int.SMPR2014.007
Torterolo, Pablo; Falconi, Atilio; Benedetto, Luciana; Rodriguez-Haralambides, A.; Rufo, C.; Bracesco, N.; “Yerba Mate: efectos sobre la vigilia y el sueño”, An. Facultad Med (Univ. Repub. Urug.) 2014: 1(1)28-40; ISSN: 2301-1254; 31/7/2014, http://www.anfamed.edu.uy/index.php/rev/article/view/68
Altesor, P., García, A., Font, E., Rodriguez-Haralambides, A., Vilaró, F., Oesterheld, M., Soler, R., Gonzalez, A.; “Glycoalkaloids of Wild and Cultivated Solanum: Effects on Specialist and Generalist Insect Herbivores”, J. Chem. Ecology 2014, 40 :566-608, DOI 10.1007/s10886-014-0447-8
Saiz, C., Castillo, V., Fontán, P., Bonilla, M., Salinas, G., Rodriguez-Haralambides, A., Mahler, S.G.; “Discovering Echinococcus granulosus Thioredoxin Glutathione Reductase inhibitors through site-specific Dynamic Combinatorial Chemistry”, Molecular Diversity 2014, 18(1), 1-12, DOI: 10.1007/s11030-013-9485-3
Umpiérrez-Failache, M., Garmendia, G., Pereyra, S., Rodríguez-Haralambides, A., Ward, T.J., Vero, S. ; “Regional differences in species composition and toxigenic potential among Fusarium head blight isolates from Uruguay indicate a risk of nivalenol contamination in new wheat production areas”, Intern. J. Food Microbiol. 2013, 166 (1), 135-140
Possi-Pezzali, T., Chigome, S., Rodriguez-Haralambides, A., Torto, N. ; Evaluation of electrospun fibers as solid phase extraction sorbent for sample preparation in HPLC-MS/MS confirmatory doping control analysis of dexamethasone and betamethasone. Anal. Methods, 2013, 5 (16), 4230-4237
Varela, J., Lavaggi, M.L., Cabrera, M., Rodríguez, A., Miño, P., Chiriboga, X., Cerecetto, H., González, M.; “Bioactive-guided identification of labdane terpenoids from aerial parts of Aristeguietia glutinosa Lam. as anti-Trypanosoma cruzi agents”, Nat. Prod. Comm. 2012, 7(9), 1139-1142
Baruffaldi, L., Costa, F.G., Rodriguez, A., Gonzalez, A.; “Chemical Communication in the Wolf spider Schizocosa malitiosa: Evidence of a female contact sex pheromone and persistence in the field”, J. Chem. Ecology 2010, 36(7), 759-767
Boiani, M., Merlino, A., Gerpe, A., Porcal, W., Croce, F., De Paula, S., Rodríguez, M.A., Cerecetto, H., Gonzalez, M.; “o-Nitroanilines as major metabolic products of anti-Trypanosoma cruzi 5-phenylethenylbenzofuroxans in microsomal and cytosolic fractions of rat hepatocytes and in whole parasitic cells”, Xenobiotica 2009, 39(3), 236-248
Betancor, L., Schelotto, F., Martinez, A., Pereira, M., Algorta, G., Rodríguez, M. A., Vignoli, R., Chabalgoity, J.A., “Random amplified polymorphic DNA and phenotyping analysis of Salmonella enterica serovar enteritidis isolates collected from humans and poultry in Uruguay from 1995 to 2002”, J. Clin Microbiol. 2004, 42(3), 1155-62.
Rodríguez, M. A.; Yost, R.A.; “Interpretation of Electrospray Mass Spectra of Bile Acids and Related Molecules”, R. Comm. Mass Spectrometry 2000, 14, 1398-1403
McDevitt, V.L.; Rodríguez, A.; Williams, K.R.; “Analysis of Soft Drinks: UV Spectrophotometry, Liquid Chromatography and Capillary Electrophoresis”, J. Chem. Ed. 1998, 75, 625-629.
Rodríguez, A.; Barrera-Arellano, D.; Grompone, M.A.; "Estabilidad oxidativa de aceite de hígado de merluza", Grasas y aceites 1993, 44, 270-273, ISSN 0017-3495; http://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/1078/1088
Current profession
Current professional activities type:ResearchTeachingAdjunct Professor at the "Instituto Polo Tecnologico de Pando", in the Chemistry Faculty, Universidad de la Republica, Uruguay. I teach graduate and undergraduate level courses, and work in reseach projects mainly in joint venture with local industry.
Affiliations
American Society of Mass SpectrometryBrMassPresentation given
2016Leveraging our Southern cultural roots through mass spectrometry: what is “yerba mate”?Rio de Janeiro, BrasilEvent: 1st IberoAmerican, VI Brazilian Conference on Mass Spectrometry2014Desafíos Analíticos en la detección de toxinas emergentesMontevideo, UruguayEvent: III Congreso Uruguayo de Química Analítica2009MS Tools in Racehorse Doping ControlCampinas, BrasilEvent: Bruker Users Meeting, III BrMass -
Other Awards
Jul 2010OPCW Laboratory Assistance ProgramSouth-South cooperation project: we received the visit of Dr. Nelson Torto (Rhodes University, South Africa), and his student Bellah Pule.May 2011OPCW FellowshipSouth-South cooperation project: My student Tania Possi visited Dr. Torto's laboratory and I visited with them as well. The project sought to develop new analytical methods according to green chemistry principles. A scientific publication resulted from this efforts.Mar 2005CSIC Research and Development ProjectsThe project: “Herramientas genómicas y proteómicas para el estudio de diversidad entre cepas de Salmonella asociadas a Enfermedad Transmitida por Alimentos", was financed during 2005-2007. The project had two PIs, (Laura Betancor and I), working at the Instituto de Higiene, Facultad de Medicina, Universidad de la Repubica, Uruguay.